Challenging a Theory
To the Editor:
The Doctor’s World column “New Book Challenges Theories of AIDS Origin” on Nov. 30 describes the hypothesis that H.I.V., the virus that causes AIDS, was initially transmitted to humans during the first large-scale trials of oral polio vaccine in what was then the Belgian Congo. Although we are not named in the article, it is common knowledge in the scientific community that we conducted those trials. The hypothesis is based on the suggestion in a recently published book that we used chimpanzee cells to prepare the vaccine, and that these cells were, unknown to us, contaminated with a precursor of the human AIDS virus.