A review by Robin A. Weiss*
The River: A Journey to the Source of HIV and AIDS
by Edward Hooper
Little, Brown, New York, 1999. 1104 pp. $35. ISBN 0-316-37261-7. Penguin, London, 1999. 1104 pp. £25. ISBN 0-7139-9335-9.
Science, 12 November 1999; Volume 286, pp. 1305-1306
Thanks to immunization, polio like smallpox may soon be eradicated. But did the trials of early polio vaccines trigger AIDS? The central thesis of Edward Hooper’s new book, The River, is that they did. Hooper argues that both AIDS viruses, HIV-1 and HIV-2, first infected humans via contaminated oral poliovirus vaccines (OPV). He claims these vaccines were grown in kidney cell cultures derived in the 1950s from chimpanzees and sooty mangabeys, respectively, that were infected with simian immunodeficiency viruses (SIVs). Although this notion has been explored before, no one previously has researched the history of polio vaccine trials and early AIDS cases so exhaustively. Hooper builds up layer upon layer of circumstantial evidence and plausible conjecture, until he declares: “The reader must make up his mind or her mind. I have made up mine.” Yet after having read his 858 pages of text and 175 pages of notes and references, I remain undecided on the origins of HIV.
Continue reading “Is AIDS Man-Made?”